CASE REPORT • Notching into a Diagnosis—Incorporating Doppler Interrogation into Point-of-Care Ultrasonography to Diagnose a Submassive Pulmonary Embolism.

Image of pulmonary embolism Pericardial Tamponade PE McConnels sign diagnostic ultrasonography computed tomography pulmonary angiography    Online PoCUS Training

CASE REPORT • Notching into a Diagnosis—Incorporating Doppler Interrogation into Point-of-Care Ultrasonography to Diagnose a Submassive Pulmonary Embolism.

Source: CASE: Cardiovascular Imaging Case Reports. 2022;6(6):250-253


Often, patients with pulmonary embolism (PE) present with nonspecific symptoms. This, in turn, pose a diagnostic dilemma. The authors present in this case report a case of submassive PE diagnosed in a patient utilizing point-of-care ultrasonography (POCUS) in the emergency department (ED).

Case presentation

A 69-year-old woman with no known medical illnesses presented to the ED with a history of lethargy and reduced effort tolerance over the past 3 months. She denied chest pain, dyspnea, or palpitations during that period. However, due to the COVID-19 pandemic and fear of being hospitalized she had delayed seeking medical attention.

Vital signs were within normal limits, and she denied being short of breath. However, her oxygen saturation was 94% on room air and respiratory rate was 18 breaths per minute. precordium and chest examination were unremarkable. Electrocardiogram revealed sinus rhythm with no evidence of tachycardia, bundle branch blocks, or right ventricular (RV) strain. chest radiograph demonstrated hilar shadowing suggestive of engorged pulmonary arteries.

Cardiac POCUS demonstrated normal left ventricular systolic function with no regional wall motion abnormalities and estimated left ventricular ejection fraction of 55%-60%. There was biatrial and right ventricular (RV) dilatation. In addition, there was flattening of intraventricular septal throughout diastole. RV fractional area change was 30%, and tricuspid annular plane systolic excursion was 1.55 cm and the presence of the McConnel’s sign.

Doppler investigation demonstrated peak velocity across the tricuspid valve of 3.7 m/sec, with a pulmonary regurgitation end-diastolic peak velocity of 2.0 m/sec.

Pulsed-wave Doppler interrogation across the pulmonary valve revealed mid-systolic notch (MSN), suggestive of raised pulmonary pressures, with a pulmonary ejection acceleration time of 56 msec.

Findings were suggestive of acute PE, prompting computed tomography pulmonary angiography, which revealed submassive main pulmonary artery embolus, extending down into the right pulmonary artery, upper lobar artery, and descending interlobar arteries.

Since the patient was stable hemodynamically, she was started on anticoagulation and was monitored as an inpatient for several days.


The authors concluded that although the trifecta of POCUS findings suggestive of PE (i.e., McConnel’s sign, MSN, and 60/60 sign) may not always exist concurrently, their presence should be actively sought by clinicians.

They further commented that while not all POCUS systems are equipped with spectral Doppler modality (e.g. in handheld devices), they suggest to use Doppler in the assessment of PE whenever possible.